This issue generally impacts users on MacOS.

There are two things that will correct this issue:
  • Change the resolution from the options panel (shortcut key: O). From there select any other resolution than the current one. Check to see if the clicks register correctly, then you can return back to original resolution and the issue should be fixed.
  • Adjust the native resolution on your MacOS to a different resolution, check to see if the clicks register correctly, then switch back to the original resolution and the issue should be fixed.